Wednesday, 18th October 12th Australian Peptide Conference 2017

• The role of Nav1.6 in peripheral pain pathways: insights from the subtype-selective scorpion toxin Cn2 - Irina Vetter
• Mapping peptide binding epitopes, and receptor conformational changes, using thermostabilised G protein-coupled receptors and NMR - Daniel J Scott
• Structural Insights into Class B GPCR peptide binding, activation and signalling. - Denise Wootten
• Pharmacology of nature-derived neuropeptide ligands - Christian W Gruber
• Ligands, Signalling and Trafficking of the Chemerin/CMKLR1-System - Annette Beck-Sickinger

• Development of Anticancer Agents from Naturally Occurring Cyclic Peptides - Tao Ye
• Silylated peptides containing chemical hydrogels : modular bioinks for 3D bioprinting - Gilles Subra
• A toolbox of double-click bioorthogonal linkers for accessing diverse macrocyclic therapeutic peptides - Yu Heng Lau
• Novel coupling reagent combinations for the synthesis of challenging peptides - Cyf Ramos-Colon
• Design and discovery of potent N-peptide HIV-1 fusion inhibitors - Keliang Liu

• Cyclosporine A and the wiggles - Conan K Wang
• pH-triggered membrane permeabilizing peptides - Kalina Hristova
• Structural basis of defensin mediated membrane attack - Marc Kvansakul
• Functional penetrating peptides - a new type of cell penetrating peptide for efficient drug delivery into mammalian cells - Tatjana Heinrich
• Redesigned spider peptide with antimicrobial, anticancer and cell penetration properties - Sónia T. Henriques

Wines kindly sourced by

• NanoBRET^TM assay for monitoring of ligand binding to GPCRs in live cells, using the CLARIOstar® and the PHERAstar® platereaders. - John Abbenante
• Spider toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel Na_V1.7 - Akello J Agwa
• Prediction of disulfide bond connectivity and configuration based on chemical shifts - David A Armstrong
• Bioactive and stabilized cationic peptide capped metallic nanohybrid materials - Manish Mr. Bajaj
• Novel capillary-flow LC HRAM MS platform for fast targeted analysis and robust profiling of complex samples - Steve Binos
• Using chemical methods to solve an antimicrobial engima - Sean W Bisset
• Silencing Intracellular Protein-Protein Interactions with Covalent Helical Peptide Inhibitors - Aline Dantas de Araujo
• Harnessing structural conservation among serine proteases to engineer targeted inhibitors using a plant-derived cyclic peptide scaffold - Simon de Veer
• Solution NMR characterisation of β-hairpin antimicrobial peptides in lipid bilayer nanodiscs. - Ingrid Edwards
• Peptide-based antagonists of the Bcl-2-regulated apoptosis pathway - Doug Fairlie
• Improvement of oral delivery of EGFR-targeted hybrid peptide by combination with bile acid - Arong Gaowa
• Blm-pep based analogs with enhanced stimulatory capacity against human 20S proteasome - Malgorzata Gizynska
• Elucidating the Rabies Virus P-protein Axis: Roles in Pathogenicity and Therapeutic Targeting - Paul Gooley
• Design and Development of Selective AT2R Ligands - Baydaa Hirmiz
• Synthesis and Structure Activity Relationship Studies of Insulin and Relaxin-like Peptides - Mohammed Akhter Hossain
• Inhibitory effects of substrate-based BCR-ABL1 kinase inhibitors on drug-resistant chronic myeloid leukaemia cell lines - Yen-Hua Huang
• Phospholipid-mediated oligomerization of defensins induces fungal and tumour cell lysis - Mark Hulett
• Structural and functional determinants for antimicrobial activity of sheep myeloid antimicrobial peptide-18 (SMAP-18) - Bomi Jung
• Identification of a cyclotide antagonist at the corticotropin-releasing factor type 1 receptor - Peter Keov
• Synthesis of N^α -Fmoc-L-fluoroacetyl lysine for crosslinking of two functional groups in the context of close proximity provided by a peptide-protein complex - Marco Jan Klein
•   Stability tests of eye drops containing PACAP - Anita K. Kovacs
• β‑peptide self-assembly as a new strategy for in situ bacterial detection and inhibition - Ketav Kulkarni
• Psd2 pea defensin’ preference for mimetic membranes rafts enriched with glucosylceramide and ergosterol - Eleonora Dr Kurtenbach
• Development of novel relaxin-3 analogues for blood-brain barrier penetration - Han Siean Lee
• Proton conduction in a tyrosine-rich peptide/manganese oxide hybrid nanofilm - Jaehun Lee
• Global Analysis of O-GlcNAc Modification on alpha-Synuclein - Paul Levine
• Design and Synthesis of Xanthone-based Peptidomimetics as Antifungal Agents to Combat Fungal Resistance - Shuimu Lin
• Enhanced binding of the SOCS2 SH2-domain to phosphorylated targets by a novel exosite peptide - Edmond Linossi
• Understanding structure, self-assembly and biological activity of natural cyclic lipodepsipeptides by synthetic modification - Annemieke Madder
• Identification of neuropeptide homologues in animal venoms using hidden markov models - Helen Mendel
• Multivalent Ligand Design – Chemistry and Applications - Markus Muttenthaler
• Peptide-based two-dimensional materials - Ki Tae Nam
• Glycocin F: A glycosylated Cs α/α peptide with a novel antimicrobial activity - Gillian Norris
• Peptide BDNF mimetics with central and peripheral nervous system actions - Susan E Northfield
• Non-covalent sulfur-oxygen interactions control conformation in a peptidomimetic that disrupts islet amyloid polypeptide fibrillation  - Hayden J Peacock
• High throughput screening of large peptide libraries to identify drug specific formulation-additives or transporters - Dario Remmler
• Polyunsaturated fatty acid-derived lipid mediators: their stability and detection in human plasma and the effect of a single dose of aspirin on their levels in healthy volunteers - Eileen Ryan
• Recombinant C-amidated antimicrobial peptide structural studies in whole bacteria using DNP solid-state NMR - Marc-Antoine Sani
• Separation of complex peptide mixtures with displacement chromatography - Hartmut Schlueter
• Targeted delivery of cyclotides via conjugation to a nanobody - Christina I Schroeder
• Polymer-based peptide vaccine delivery systems. - Mariusz Skwarczynski
• Ticks from Diverse Genera Encode Chemokine-Inhibitory Evasin Proteins - Martin J Stone
• RaPID selection of macrocyclic peptides targeting ROR1 - Rhys Taylor
•  Synthesis and characterisation of trefoil factor 3 loop mimetics    - Hue N. T. Tran
• Synthesis and Functional Evaluation of Anti-Thrombotic Proteins Bearing Tyrosine Sulfation - Emma E Watson
• Proteases in venom from jellyfish Nemopilema nomurai - Huahua Yu
• Metalloantibiotics: old battles, new tricks. - Zyta M Ziora
• A novel bifunctional chimera targeting both HIV-1 Env and host cell co-receptor - Lirui Song
• Biodistribution evaluation of ¹⁸⁸Re-liposome-SP90 in breast cancer solid tumor model - Liang-Cheng Chen
• Identification and characterization of CHH-like neuropeptide receptors in the blackback land crab (Gecarcinus lateralis) molting gland transcriptome - Nhut Tran
• Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer - Xiaosa Wu
• Tracking and reporting synthetic peptide impurities with a cost-effective single quadrupole mass detector for improved confidence in analysis - Heather Patsiouras
• Evaluation of a novel tandem quadrupole mass spectrometer for the multi-point internal calibration analysis of peptides - Heather Patsiouras
• Enhancing vancomycin potency via complexation with silver ions - Zyta M Ziora
• Hydroxylamine derivatives as new compounds to treat antibiotic bacterial resistance - Laia Miret Casals